The Spice Corridor

The Spice Corridor is the most well traveled waterway on the continent, despite its small size. Ships must pass in lanes that are designated by buoys. It is named the Spice Corridor for the same reason that the cities built on its banks are known as the Spice Cities. Tremendous amounts of spices and other exotic goods pass through the ports. The waters are heavily patroled, making piracy impossible in such an area.
"Enough gold can be made on a single good run of the Spice Corridor to set a man for life." - Guildmaster Erthar