Elturel is conquered by a powerful vampire Lord leading an army of undead.
Torimesh the druid starts and finishes construction of Insight Park in Baldur's Gate.
The High Observer of Torm in Elturgard orders that the Reaching Woods are barricaded in order to stem the never ending tide of gnolls and goblins that seem to emerge from it.
Dagult Neverember, Open Lord of Waterdeep, arrives in Neverwinter and starts reconstruction of the city.
The entire garrison and staff manning Fort Morninglord in Elturgard disappear overnight as the castle itself changes into a place of mystery. All the keep's stones are blackened and the windows and doors are fused shut. The High Observer orders the keep shut.
Ao the Overgod begins the Second Sundering as a way to overcome the ravages of the Spellplague of the years before.
Grand Duke Abdel Adrian of Baldur's Gate is challenged by Viekang, the last remaining Bhaalspawn in the region. One killed the other and ascended to become an avatar to Bhaal, then proceeded to kill hundreds of civilians before the Flaming Fist was able to subdue it.
The town of Greenest in the Western Heartlands is overrun by the Cult of the Dragon. It is the first time the Cult organizes in such a way, and marks the start of the Tyranny of Dragons.
The city of Elturel is destroyed, leaving nothing behind but a fiery crater.