The Big Game

Four characters from all around the Sword Coast each have an artifact in their possession. They are drawn for unknown reasons to Mintarn, where they meet and realize the four artifacts connect to form a magical compass. 
The compass points the way to two shrines, containing the Eye and Hand of Vecna, respectively. 
Meanwhile, Tyranthraxus has risen back through the Pool of Radience and is seeking the Eye and Hand for his own power and purpose. 
Another faction, with the Blood Hunter Elamaris Cithreth as its agent, is seeking the Eye and Hand as well as the Sword of Kas in order to destroy them once and for all.
The characters must retrieve the compass, travel to the four Sea Towers in order to awaken its power and then hunt down the Eye and Hand of Vecna.