Poisons

Used most often by The Merciful, murder is just one use for poisons.

[The poisons from the Dungeon Master's Guide are also allowed.]

Common poisons are simple and easily used by anyone with ill intent. However, there are more powerful, strange, and rare poisons to be had for those who know how. These poisons are almost exclusively used by The Merciful, the highly secretive worldwide Assassins' Guild. The poisoners who aren't among the Merciful tend to be rogue alchemists, amoral herbalists, and certain skilled mercenaries.

Medusa's Friend

Contact

Made from a sticky, sap-like substance excreted by certain Chultan slime molds, Medusa’s Friend is sometimes used by Chultan tabaxi and firbolg tribes to take down particularly large or dangerous creatures.

DC 13 CON Saving Throw On a failed save, the creature is poisoned for 1 minute. The poisoned creature is paralyzed. The creature can repeat the saving throw at the end of each of its turns, ending the effect on a success.

Nightmare Root

Ingested
Made from the root tendrils of dream’s end, a blue-spotted purple mushroom about an inch across that grows in small clusters. When ground into a paste, it can be mixed into food or drink without significantly altering the taste, color, or odor. It does leave a faint residue like fine sand. Those who consume the root paste are haunted by their greatest fears upon falling asleep.
DC 15 CON Saving Throw On a failed save, the creature’s sleep is haunted by a combination of their greatest fears and everything they’re ever done wrong. An affected creature cannot benefit from long rests and gains a point of exhaustion at the beginning of the next day. The poison leaves the creature’s system 24 hours after ingestion.

Taltossa’s Breath

Inhaled
Made from the spores of the corpseflower, a large orange mushroom with a strong smell of rancid meat.
The spores are blown into the face and burn when inhaled, cause bleeding sores, vomiting and severe joint pain. Sometimes used as a calling card by certain sects of The Merciful (the continental assassin’s guild) to publicly mark a target for later assassination. Named for Taltossa, Stranger to All god of murder, assassination and death as well as darkness and night.
DC 15 CON Saving Throw On a failed save, they take 6 (1d12) poison damage and are poisoned for 24 hours. On a successful save, they take half damage and are not poisoned.